Rethinking Alzheimer’s at the cellular level

Aerobyx is developing a new approach to Alzheimer’s focused on how brain cells produce and use energy.

The Challenge

A Different Approach

What We’re Building

Alzheimer’s disease affects millions worldwide, yet available treatments don’t stop its progression. For decades, research has focused on amyloid plaques and tau tangles with limited success.

Emerging research suggests Alzheimer’s may begin with disruptions in how brain cells generate energy. Aerobyx is focused on mitochondrial function and neuronal metabolism, processes that may play a role early in disease development.

Aerobyx is developing a bioenergetic therapy designed to support cellular energy function in the brain. This approach aims to address underlying disease mechanisms rather than focusing solely on symptoms.

Why It Matters

Several brain MRI scans displayed on a computer screen, showing axial views of the brain in shades of gray and white.

Targets a potential root cause of disease

Person in a white lab coat holding a model of a human brain in a laboratory setting, with a DNA double helix model and laboratory equipment visible in the background.

Builds on established scientific research

A person working on a puzzle shaped like a human head silhouette, placing a puzzle piece into the puzzle on a wooden surface.

Opens new possibilities for treating neurodegenerative conditions